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Mediterranea SEA₁₈ New Generation HPLC Column

Teknokroma's Mediterranea sea₁₈ column provides a performance level that, until now, has not been reached in efficiency, inertness, pH-robustness, reproducibility and reliability. Mediterranea sea₁₈ columns simplify and make your HPLC work more pleasant.

Teknokroma has been concentrated on obtaining the best silica particle in the market. The silica particle on which the mediterranea sea₁₈ column is based is the result of an optimisation process.
It begins with extremely pure, low metal content, silica from which a perfectly spherical, rigid and inert particle is obtained.

SEA - Surface Enhanced Accessibility
More than 98% of the silica surface area responsible forchromatographic separation of the sample is found inside the particle - within the pores. This explains the extreme importance of obtaining a very homogeneous pore distribution and the least possible number of nanopores.

The pore distribution of the mediterranea sea₁₈ column has been optimised by our own proprietary process called Surface Enhanced Accessibility (sea). The Surface Enhanced Accessibility "porification" process creates high surface area without losing silica structural strength, chemical resistance, chemical inertness and high load capacity. Surface Enhanced Accessibility also ensures that practically 100% of the internal packing surface has been chemically bonded, endcapped, and is accessible to compounds being separated.

Moreover, the Surface Enhanced Accessibility of mediterranea sea₁₈ ensures the maximum transfer speed of the solutes between the stationary and mobile phases, resulting in a greater separation efficiency.

MED - Multifunctional Endcapping Deactivation
The endcapping process is a critical step in obtaining a perfectly deactivated mediterranea sea₁₈ column. Teknokroma's proprietary Multifunctional Endcapping Deactivation (MED) technologymaximizes surface-bonding, blocking practically all the active centres that may have remained on the surface of the silica afterbonding the C18 chains.

Thanks to MED technology, the mediterranea sea₁₈ column enjoys an unusual low level of silanol activity - helping you to obtain symmetrical peaks from even the most basic and acidic pharmaceuticals and their metabolites.

Mediterranea sea₁₈ bonding chemistries will help you to achieve an extraordinary resistance and column lifetime when running at extreme pH levels.
Moreover, the mediterranea sea₁₈ column has been designed to show an excellent retention of polar compounds in a 100% aqueous environment without the problems of unwanted interactions which inefficiently endcapped conventional packings produce.