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Europa HPLC Columns for Peptides and Proteins

The Europa HPLC columns for peptides and proteins, provide the best performance and unsurpassed efficiency, reliability and reproducibility.

Manufactured using novel proprietary technologies, analytical and preparative Europa columns are simply the best reverse phase columns available today.

Teknokroma's Europa Columns are uniquely designed with optimized pore size distribution; 120Å for Peptide and 300Å for the Protein Columns.

We invite you to try Europa C18 when you experience less than satisfactory results with your favourite column.

Teknokroma has been concentrated on obtaining the best silica particle in the market. The silica particle on which the Europa C18 column is based is the result of an optimisation process.
It begins with extremely pure, low metal content, silica from which a perfectly spherical, rigid and inert particle is obtained.

Furthermore, the proprietary "porification process" (Surface Enhanced Accessibility, SEA) for Europa C18 silica has achieved high surface area without sacrificing important properties like physical resistance and high loading capacity - making it ideal for preparative-scale processing.

SEA - Surface Enhanced Accessibility
More than 98% of the silica surface area responsible for chromatographic separation of the sample is found inside the particle - within the pores. This explains theextreme importance of obtaining a very homogeneous pore distribution and the least possible number of nanopores.

The pore distribution of the Europa C18 column has been optimised by Teknokroma's proprietary process called Surface Enhanced Accessibility (SEA). The Surface Enhanced Accessibility "porification" process creates high surface area without losing silica structural strength, chemical resistance, chemical inertness and high load capacity. Surface Enhanced Accessibility also ensures that practically 100% of the internal packing surface has been chemically bonded, endcapped, and is accessible to compounds being separated.

Moreover, the Surface Enhanced Accessibility of Europa C18 ensures the maximum transfer speed of the solutes between the stationary and mobile phases, resulting in a greater separation efficiency.

MED - Multifunctional Endcapping Deactivation
The endcapping process is a critical step in obtaining a perfectly deactivated mediterranea sea18 column. Teknokroma's proprietary Multifunctional Endcapping Deactivation (MED)technology maximizes surface-bonding, blocking practically all the active centres that may have remained on the surface of the silica after bonding the C18 chains.

Thanks to MED technology, the Europa columns column enjoys an unusually low level of silanol activity - helping you to obtain symmetrical peaks from even the most basic and acidic pharmaceuticals and their metabolites.

All Teknokroma columns work with 0-100% organic, aswell as aqueous mobile phases, without any limitations. Just select a column designated for your type of sample to achieve superior results.

Specifications:

• Ultra high purity totally spherical silica gel provide a high resolution and excellent peak shape
• High loading capacity of crude proteins
• High density bonding for extreme performance proprietary fully end-capped silica
• Stable, featuring extended acidic and basic conditions
• Silica properties: ultra pure and totally spherical narrow distribution range and highdensity
• Fully end-capped silica
• Porous Size: 120 / 300Å narrow particle size distribution
• Surface Area m2/g 100
• % of Carbon 7 %
• Packed with 5µm sized silica particles
• Available as C4, C8, and C18 columns

Microbore Columns are available in: 0.21, 0.30 cmI.D.

Analytical Columns in: 0.40 and 0.46cm I.D.

Semi-Prep in: 0.70-1.0cm

Prep Columns in: 2.1cm and larger diameter by request